Sodium hydrosulfide increases glutathione synthesis in cardiac muscle cell line HL-1 under hyperglycemia and hyperlipidemia

Sodium hydrosulfide increases glutathione synthesis in cardiac muscle cell line HL-1 under hyperglycemia and hyperlipidemia

Objective To investigate sodium hydrogen sulfide(NaHS) with function of regulating glutathione(GSH) synthesis to reduce reactive oxygen species(ROS) production in type 2 diabetic cardiomyopathy (DCM). Methods Mouse cardiomyocyte cell line HL-1 was incubated with high concentration of glucose (HG:40...

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Bibliographic Details
Main Author: ZHANG Weicai, LIU Siren, WANG Shangnong
Format: Article
Language:zho
Published: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2024-01-01
Series:Jichu yixue yu linchuang
Subjects:
diabetic cardiomyopathy|hydrogen sulfide|glutathione|nuclear factor erythroid-derived 2-related factors 2(nrf2)|muscle specific ring finger protein 1(murf1)
Online Access:http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2024-44-1-69.pdf

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http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2024-44-1-69.pdf

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