Unfolding Individual Domains of BmrA, a Bacterial ABC Transporter Involved in Multidrug Resistance

The folding and stability of proteins are often studied via unfolding (and refolding) a protein with urea. Yet, in the case of membrane integral protein domains, which are shielded by a membrane or a membrane mimetic, urea generally does not induce unfolding. However, the unfolding of α-helical memb...

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Bibliographic Details
Main Authors: Kristin Oepen, Veronika Mater, Dirk Schneider
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/6/5239