Drug target prediction through deep learning functional representation of gene signatures

Drug target prediction through deep learning functional representation of gene signatures

Abstract Many machine learning applications in bioinformatics currently rely on matching gene identities when analyzing input gene signatures and fail to take advantage of preexisting knowledge about gene functions. To further enable comparative analysis of OMICS datasets, including target deconvolu...

Full description

Bibliographic Details
Main Authors: Hao Chen, Frederick J. King, Bin Zhou, Yu Wang, Carter J. Canedy, Joel Hayashi, Yang Zhong, Max W. Chang, Lars Pache, Julian L. Wong, Yong Jia, John Joslin, Tao Jiang, Christopher Benner, Sumit K. Chanda, Yingyao Zhou
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-46089-y

Internet

https://doi.org/10.1038/s41467-024-46089-y

Similar Items