Regulation of the cardiomyocyte transcriptome <it>vs </it>translatome by endothelin-1 and insulin: translational regulation of 5' terminal oligopyrimidine tract (TOP) mRNAs by insulin
<p>Abstract</p> <p>Background</p> <p>Changes in cellular phenotype result from underlying changes in mRNA transcription and translation. Endothelin-1 stimulates cardiomyocyte hypertrophy with associated changes in mRNA/protein expression and an increase in the rate of p...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-05-01
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Series: | BMC Genomics |
Online Access: | http://www.biomedcentral.com/1471-2164/11/343 |