Strontium ranelate inhibits wear particle-induced aseptic loosening in mice

The imbalance between bone formation and osteolysis plays a key role in the pathogenesis of aseptic loosening. Strontium ranelate (SR) can promote bone formation and inhibit osteolysis. The aim of this study was to explore the role and mechanism of SR in aseptic loosening induced by wear particles....

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Bibliographic Details
Main Authors: Tianxiang Geng, Shouxuan Sun, Haochen Yu, Haohui Guo, Mengxue Zheng, Shuai Zhang, Xi Chen, Qunhua Jin
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2018-07-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000900605&lng=en&tlng=en