Strontium ranelate inhibits wear particle-induced aseptic loosening in mice

Strontium ranelate inhibits wear particle-induced aseptic loosening in mice

The imbalance between bone formation and osteolysis plays a key role in the pathogenesis of aseptic loosening. Strontium ranelate (SR) can promote bone formation and inhibit osteolysis. The aim of this study was to explore the role and mechanism of SR in aseptic loosening induced by wear particles....

Full description

Bibliographic Details
Main Authors:	Tianxiang Geng, Shouxuan Sun, Haochen Yu, Haohui Guo, Mengxue Zheng, Shuai Zhang, Xi Chen, Qunhua Jin
Format:	Article
Language:	English
Published:	Associação Brasileira de Divulgação Científica 2018-07-01
Series:	Brazilian Journal of Medical and Biological Research
Subjects:	Strontium ranelate Aseptic loosening Sclerostin Bone remodeling Canonical Wnt pathway
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000900605&lng=en&tlng=en

Similar Items

Strontium ranelate in the treatment of postmenopausal osteoporosis: results of administration in clinical practice
by: N V Toroptsova, et al.
Published: (2008-06-01)

Pathogenetic treatment with strontium ranelate in women with postmenopausal osteoporosis
by: Olga Borisovna Yershova
Published: (2010-12-01)

POSSIBILITY OF BONE METABOLISM MODULATOR (STRONTIUM RANELATE) USAGE FOR THE TREATMENT OF WOMEN WITH POSTMENOPAUSAL OSTEOPOROSIS AND ARTERIAL HYPERTENSION
by: N. J. Hozjainova, et al.
Published: (2016-01-01)

THE PLACE OF STRONTIUM RANELATE IN THE TREATMENT OF PATIENTS WITH OSTEOPOROSIS (RESULTS OF THE MARC PROGRAM)
by: O. A. Nikitinskaya, et al.
Published: (2018-09-01)

STRONTIUM RANELATE IS THE DRUG OF CHOICE IN THE TREATMENT OF OSTEOPOROSIS
by: Nataliya Vladimirovna Toroptsova
Published: (2010-09-01)

STRONTIUM RANELATE IS THE DRUG OF CHOICE IN THE TREATMENT OF OSTEOPOROSIS
by: Nataliya Vladimirovna Toroptsova
Published: (2010-09-01)

Prophylactic and Therapeutic Use of Strontium Ranelate Reduces the Progression of Experimental Osteoarthritis
by: Thiago A. Rodrigues, et al.
Published: (2018-09-01)

Comparison of the Effects of Strontium Ranelate and Raloxiphene on Bone Mineral Density in Postmenopausal Osteoporosis - Original Investigation
by: Figen Yılmaz, et al.
Published: (2009-04-01)

Comparison of Effectiveness of Strontium Ranelate and Alendronate Sodium in Postmenopausal Osteoporosis - Original Investigation
by: Kurtuluş Kaya, et al.
Published: (2009-12-01)

PATHOGENESIS OF OSTEOARTHRITIS AND SUBSTANTIATION OF THE USE OF STRONTIUM RANELATE
by: Elena Mikhailovna Zaitseva, et al.
Published: (2014-02-01)

Strontium ranelate is a drug to treat osteoarthrosis
by: Oksana Anatolyevna Nikitinskaya
Published: (2013-03-01)

Strontium ranelate as a possible disease-modifying osteoarthritis drug: a systematic review
by: T.A. Rodrigues, et al.
Published: (2018-06-01)

Evaluation Aseptic Loosening of Primary Hip Arthroplasty
by: Hasan H Al-Abboodi
Published: (2020-09-01)

Effect of Strontium Ranelate on Condylar Growth during Mandibular Advancement in Rats
by: Hasan Camcı, et al.
Published: (2020-12-01)

The Short-Term Effects of Strontium Ranelate on Pain and Bone Mineral Density in Postmenopausal Women with Osteoporosis
by: Halil Koyuncu, et al.
Published: (2012-08-01)

Cytotoxicity Analysis of Strontium Ranelate on Cultured Human Periodontal Ligament Fibroblasts: A Preliminary Report
by: Kürşat Er, et al.
Published: (2008-08-01)

Effect of strontium ranelate and cerium oxide addition in the diet on egg production and eggshell quality in laying hen
by: PAYAM SADQ SABIR, et al.
Published: (2023-01-01)

Reversed phase HPLC for strontium ranelate: Method development and validation applying experimental design
by: Kovács Béla, et al.
Published: (2018-06-01)

Macrophages in aseptic loosening: Characteristics, functions, and mechanisms
by: Yehao Cong, et al.
Published: (2023-03-01)

Strontium ranelate enriched Ruminococcus albus in the gut microbiome of Sprague–Dawley rats with postmenopausal osteoporosis
by: Xiao Xiao, et al.
Published: (2023-11-01)

The Comparison of the Effect of Risedronate and Strontium Ranelate on Bone Mineral Density in Postmenopausal Women
by: Figen Yılmaz, et al.
Published: (2012-08-01)

Therapeutic intervention for wear debris-induced aseptic implant loosening
by: Ke Ren, et al.
Published: (2013-04-01)

A new contralateral atypical femoral fracture despite sequential therapy with teriparatide and strontium ranelate
by: Hanh H Nguyen, et al.
Published: (2017-06-01)

Evaluation of Biocompatibility of New Osteoplastic Xenomaterials Containing Zoledronic Acid and Strontium Ranelate
by: Maksim V. Stogov, et al.
Published: (2023-06-01)

Aseptic loosening around total joint replacement in humans is regulated by miR-1246 and miR-6089 via the Wnt signalling pathway
by: Yi Deng, et al.
Published: (2024-01-01)

Effect of strontium ranelate and cerium oxide addition in the diet on bone quality and expression level of osteocalcin and alkaline phosphatase genes in broiler chicken
by: Payam Sadq Sabir, et al.
Published: (2023-07-01)

Strontium ranelate treatment in a postmenopausal woman with osteonecrosis of the jaw after long-term oral bisphosphonate administration: a case report
by: Pan WL, et al.
Published: (2017-07-01)

Strontium Ranelate Inhibits Osteoclastogenesis through NF-κB-Pathway-Dependent Autophagy
by: Dongle Wu, et al.
Published: (2023-03-01)

Facilitated and Controlled Strontium Ranelate Delivery Using GCS-HA Nanocarriers Embedded into PEGDA Coupled with Decortication Driven Spinal Regeneration
by: Chiang CW, et al.
Published: (2021-06-01)

Nano wear particles and the periprosthetic microenvironment in aseptic loosening induced osteolysis following joint arthroplasty
by: Yu Xie, et al.
Published: (2023-10-01)

REVISION TOTAL HIP ARTHROPLASTY IN PATIENTS WITH ASEPTIC LOOSENING OF FEMORAL STEM (REVIEW)
by: A. V. Sementkovsky
Published: (2011-03-01)

Osteoporosis: from cost-effect characteristics to clinical efficacy and safety of strontium ranelate (bivaios)
by: Ia S Dydykina, et al.
Published: (2008-05-01)

Comparison of results of revision total knee arthroplasty surgery due to septic and aseptic loosening
by: Fatih Dogar, et al.
Published: (2021-09-01)

Total hip revision in patients with isolated aseptic loosening of the acetabular component
by: Kseniia P. Zvereva, et al.
Published: (2018-12-01)

How to Prevent Aseptic Loosening in Cementless Arthroplasty: A Review
by: Dragos Apostu, et al.
Published: (2022-02-01)

Diabetes mellitus is a potential risk factor for aseptic loosening around hip and knee arthroplasty
by: Yi Deng, et al.
Published: (2023-04-01)

Nanoparticle-based model of anti-inflammatory drug releasing LbL coatings for uncemented prosthesis aseptic loosening prevention
by: Alotaibi HF, et al.
Published: (2019-09-01)

Radiographic Assessment of Aseptic Loosening of Tumor‐Type Knee Prosthesis in Distal Femur
by: Zi‐ming Li, et al.
Published: (2022-06-01)

Revision for Aseptic Loosening of Tumor Prosthesis in Lower Limbs
by: XU Hairong, et al.
Published: (2022-06-01)

Early aseptic loosening of primary total knee arthroplasty in patients with osteonecrosis of the knee: A case series
by: Ji‐Hoon Baek, et al.
Published: (2022-12-01)