Liver-Derived TGF-β Maintains the EomeshiTbetlo Phenotype of Liver Resident Natural Killer Cells

The adult human liver hosts a complex repertoire of liver resident and transient natural killer (NK) cell populations with diverse phenotypes and functions. Liver resident NK cells are CD56bright NK cells defined by a unique expression profile of transcription factors and cell surface markers (Eomes...

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Bibliographic Details
Main Authors: Cathal Harmon, Gráinne Jameson, Dalal Almuaili, Diarmaid D. Houlihan, Emir Hoti, Justin Geoghegan, Mark W. Robinson, Cliona O'Farrelly
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01502/full