Rapid progressing allele HLA-B35 Px restricted anti-HIV-1 CD8+ T cells recognize vestigial CTL epitopes.

Rapid progressing allele HLA-B35 Px restricted anti-HIV-1 CD8+ T cells recognize vestigial CTL epitopes.

The HLA-B*35-Px allele has been associated with rapid disease progression in HIV-1 infection, in contrast to the HLA-B*35-Py allele.Immune responses to two HLA-B*35 restricted HIV-1 specific CTL epitopes and their variants were followed longitudinally during early HIV-1 infection in 16 HLA-B*35+ ind...

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Bibliographic Details
Main Authors: Christian B Willberg, Keith E Garrison, R Brad Jones, Duncan A Meiklejohn, Gerald Spotts, Teri J Liegler, Mario A Ostrowski, Annika C Karlsson, Frederick M Hecht, Douglas F Nixon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2858076?pdf=render

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http://europepmc.org/articles/PMC2858076?pdf=render

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