25-Hydroxycholecalciferol Inhibits Cell Growth and Induces Apoptosis in SiHa Cervical Cells via Autocrine Vitamin D Metabolism

25-Hydroxycholecalciferol Inhibits Cell Growth and Induces Apoptosis in SiHa Cervical Cells via Autocrine Vitamin D Metabolism

Preclinical studies show that the anticancer actions of vitamin D metabolites are mediated by apoptosis, inhibition of cell proliferation and induction of cell cycle arrest. Cervical cancer cells express an autocrine vitamin D metabolising system (VDMS) comprised of a vitamin D receptor, vitamin D c...

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Bibliographic Details
Main Authors: Rivak Punchoo, Greta Dreyer, Tahir S. Pillay
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Biomedicines
Subjects:
cervical cancer
SiHa
25-hydroxycholecalciferol
apoptosis
vitamin D metabolising system
24-hydroxylase (CYP24A1)
Online Access:https://www.mdpi.com/2227-9059/11/3/871

Internet

https://www.mdpi.com/2227-9059/11/3/871

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