The JAK-STAT Pathway as a Therapeutic Strategy in Cancer Patients with Immune Checkpoint Inhibitor-Induced Colitis: A Narrative Review

The JAK-STAT Pathway as a Therapeutic Strategy in Cancer Patients with Immune Checkpoint Inhibitor-Induced Colitis: A Narrative Review

Immunotherapy has emerged as a pivotal component in the treatment of various malignancies, encompassing lung, skin, gastrointestinal, and head and neck cancers. The foundation of this therapeutic approach lies in immune checkpoint inhibitors (ICI). While ICIs have demonstrated remarkable efficacy in...

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Bibliographic Details
Main Authors: Antonietta Gerarda Gravina, Raffaele Pellegrino, Alfonso Esposito, Marina Cipullo, Mario Romeo, Giovanna Palladino, Patrizia Iodice, Alessandro Federico, Teresa Troiani
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Cancers
Subjects:
immunotherapy
immune checkpoint inhibitors
colitis
JAK-STAT
tofacitinib
immune-related adverse events
Online Access:https://www.mdpi.com/2072-6694/16/3/611

Internet

https://www.mdpi.com/2072-6694/16/3/611

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