Genetic Variants in Protein Tyrosine Phosphatase Non-Receptor Type 23 Are Responsible for Mesiodens Formation

Genetic Variants in Protein Tyrosine Phosphatase Non-Receptor Type 23 Are Responsible for Mesiodens Formation

A mesiodens is a supernumerary tooth located in the midline of the premaxilla. To investigate the genetic cause of mesiodens, clinical and radiographic examination were performed on 23 family members of a two-generation Hmong family. Whole exome sequencing (WES) or Sanger sequencing were performed i...

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Bibliographic Details
Main Authors: Ploy Adisornkanj, Rajit Chanprasit, Steven Eliason, Juan M. Fons, Worrachet Intachai, Sissades Tongsima, Bjorn Olsen, Stefan T. Arold, Chumpol Ngamphiw, Brad A. Amendt, Abigail S. Tucker, Piranit Kantaputra
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Biology
Subjects:
extra tooth
<i>PTPN23</i>
mesiodentes
mutation
phosphatase
protein expression
Online Access:https://www.mdpi.com/2079-7737/12/3/393

Internet

https://www.mdpi.com/2079-7737/12/3/393

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