FGFR3–TACC3: A novel gene fusion in cervical cancer

FGFR3–TACC3: A novel gene fusion in cervical cancer

Cervical cancer epitomizes the success of cancer prevention through the human papillomavirus (HPV) vaccine, but significant challenges remain in the treatment of advanced disease. We report the first three cases of cervical carcinoma harboring an FGFR3–TACC3 fusion, which serves as a novel therapeut...

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Bibliographic Details
Main Authors: Benedito A. Carneiro, Julia A. Elvin, Suneel D. Kamath, Siraj M. Ali, Ajit S. Paintal, Alvaro Restrepo, Emily Berry, Francis J. Giles, Melissa L. Johnson
Format: Article
Language:English
Published: Elsevier 2015-08-01
Series:Gynecologic Oncology Reports
Subjects:
FGFR translocations
FGFR-TACC3
FGFR inhibitors
Cervical carcinoma
Targeted therapy
Adenocarcinoma of the cervix
Online Access:http://www.sciencedirect.com/science/article/pii/S2352578915000430

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http://www.sciencedirect.com/science/article/pii/S2352578915000430

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