Gene-environment interaction analysis of redox-related metals and genetic variants with plasma metabolic patterns in a general population from Spain: The Hortega Study

Gene-environment interaction analysis of redox-related metals and genetic variants with plasma metabolic patterns in a general population from Spain: The Hortega Study

Background: Limited studies have evaluated the joint influence of redox-related metals and genetic variation on metabolic pathways. We analyzed the association of 11 metals with metabolic patterns, and the interacting role of candidate genetic variants, in 1145 participants from the Hortega Study, a...

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Main Authors: Marta Galvez-Fernandez, Francisco Sanchez-Saez, Arce Domingo-Relloso, Zulema Rodriguez-Hernandez, Sonia Tarazona, Vannina Gonzalez-Marrachelli, Maria Grau-Perez, Jose M. Morales-Tatay, Nuria Amigo, Tamara Garcia-Barrera, Jose L. Gomez-Ariza, F. Javier Chaves, Ana Barbara Garcia-Garcia, Rebeca Melero, Maria Tellez-Plaza, Juan C. Martin-Escudero, Josep Redon, Daniel Monleon
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Redox Biology
Subjects:
Metals
Metabolomics
Oxidative stress
Candidate genes
Gene-environment interaction
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231722000866

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http://www.sciencedirect.com/science/article/pii/S2213231722000866

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