CXCL12-induced rescue of cortical dendritic spines and cognitive flexibility

Synaptodendritic pruning is a common cause of cognitive decline in neurological disorders, including HIV-associated neurocognitive disorders (HAND). HAND persists in treated patients as a result of chronic inflammation and low-level expression of viral proteins, though the mechanisms involved in syn...

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Bibliographic Details
Main Authors: Lindsay K Festa, Elena Irollo, Brian J Platt, Yuzen Tian, Stan Floresco, Olimpia Meucci
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-01-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/49717