Biophysical Profiling of Sickle Cell Disease Using Holographic Cytometry and Deep Learning

Sickle cell disease (SCD) is an inherited hematological disorder associated with high mortality rates, particularly in sub-Saharan Africa. SCD arises due to the polymerization of sickle hemoglobin, which reduces flexibility of red blood cells (RBCs), causing blood vessel occlusion and leading to sev...

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Bibliographic Details
Main Authors: Cindy X. Chen, George T. Funkenbusch, Adam Wax
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/15/11885