Identification of the PfK13 mutations R561H and P441L in the Democratic Republic of Congo

Identification of the PfK13 mutations R561H and P441L in the Democratic Republic of Congo

Objectives: Partial artemisinin resistance, mediated by Plasmodium falciparum K13 (PfK13) mutations, has been confirmed in certain areas of East Africa that are historically associated with high-level antimalarial resistance. The Democratic Republic of Congo (DRC) borders these areas in the East. Th...

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Main Authors: Gauthier Mesia Kahunu, Sarah Wellmann Thomsen, Louise Wellmann Thomsen, Hypolite Muhindo Mavoko, Patrick Mitashi Mulopo, Emma Filtenborg Hocke, Papy Mandoko Nkoli, Vito Baraka, Daniel T.R. Minja, Andria Mousa, Cally Roper, Destin Mbongi Moke, Dieudonné Mumba Ngoyi, Eric Mukomena Sompwe, Jean Jacques Muyembe Tanfum, Helle Hansson, Michael Alifrangis
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:International Journal of Infectious Diseases
Subjects:
Democratic Republic of Congo
Antimalarial drugs
Drug resistance
Artemisinin, PfK13
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971223007877

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http://www.sciencedirect.com/science/article/pii/S1201971223007877

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