Development of dynamic kinetic resolution on large scale for (±)-1-phenylethylamine

Candida antarctica lipase B (CALB) and racemization catalyst 4 were combined in the dynamic kinetic resolution (DKR) of (±)-1-phenylethylamine (1). Several reaction parameters have been investigated to modify the method for application on multigram scale. A comparison of isopropyl acetate and alkyl...

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Bibliographic Details
Main Authors: Lisa K. Thalén, Jan-E. Bäckvall
Format: Article
Language:English
Published: Beilstein-Institut 2010-09-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.6.97