Non-Transfusion-Dependent Thalassemia: An Update on Complications and Management

Non-Transfusion-Dependent Thalassemia: An Update on Complications and Management

Patients with non-transfusion-dependent thalassemia (NTDT) experience many clinical complications despite their independence from frequent transfusions. Morbidities in NTDT stem from the interaction of multiple pathophysiological factors: ineffective erythropoiesis, iron overload (IOL), and hypercoa...

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Bibliographic Details
Main Authors: Joseph Sleiman, Ali Tarhini, Rayan Bou-Fakhredin, Antoine N. Saliba, Maria Domenica Cappellini, Ali T. Taher
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:International Journal of Molecular Sciences
Subjects:
non-transfusion dependent thalassemia
morbidity
management
ineffective erythropoiesis
iron overload
iron chelation therapy
Online Access:http://www.mdpi.com/1422-0067/19/1/182

Internet

http://www.mdpi.com/1422-0067/19/1/182

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