Bruch’s-Mimetic Nanofibrous Membranes Functionalized with the Integrin-Binding Peptides as a Promising Approach for Human Retinal Pigment Epithelium Cell Transplantation

Bruch’s-Mimetic Nanofibrous Membranes Functionalized with the Integrin-Binding Peptides as a Promising Approach for Human Retinal Pigment Epithelium Cell Transplantation

Background: This study aimed to develop an ultrathin nanofibrous membrane able to, firstly, mimic the natural fibrous architecture of human Bruch’s membrane (BM) and, secondly, promote survival of retinal pigment epithelial (RPE) cells after surface functionalization of fibrous membranes. Methods: I...

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Bibliographic Details
Main Authors: Shaocheng Wang, Siyong Lin, Bo Xue, Chenyu Wang, Nana Yan, Yueyan Guan, Yuntao Hu, Xuejun Wen
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Molecules
Subjects:
retinal pigment epithelial transplantation
integrin
peptides
electrospinning
Bruch’s membrane
immunogenicity
Online Access:https://www.mdpi.com/1420-3049/27/4/1429

Internet

https://www.mdpi.com/1420-3049/27/4/1429

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