Exogenous ANP Treatment Ameliorates Myocardial Insulin Resistance and Protects against Ischemia–Reperfusion Injury in Diet-Induced Obesity

Exogenous ANP Treatment Ameliorates Myocardial Insulin Resistance and Protects against Ischemia–Reperfusion Injury in Diet-Induced Obesity

Increasing evidence suggests natriuretic peptides (NPs) coordinate interorgan metabolic crosstalk. We recently reported exogenous ANP treatment ameliorated systemic insulin resistance by inducing adipose tissue browning and attenuating hepatic steatosis in diet-induced obesity (DIO). We herein inves...

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Bibliographic Details
Main Authors: Yuhei Oi, Tomohisa Nagoshi, Haruka Kimura, Yoshiro Tanaka, Akira Yoshii, Rei Yasutake, Hirotake Takahashi, Yusuke Kashiwagi, Toshikazu D. Tanaka, Toshiaki Tachibana, Michihiro Yoshimura
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:International Journal of Molecular Sciences
Subjects:
natriuretic peptide
diet-induced obesity
insulin resistance
ischemia–reperfusion injury
intramyocardial lipid droplet
Online Access:https://www.mdpi.com/1422-0067/23/15/8373

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https://www.mdpi.com/1422-0067/23/15/8373

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