Caenorhabditis elegans LET-413 Scribble is essential in the epidermis for growth, viability, and directional outgrowth of epithelial seam cells.

The conserved adapter protein Scribble (Scrib) plays essential roles in a variety of cellular processes, including polarity establishment, proliferation, and directed cell migration. While the mechanisms through which Scrib promotes epithelial polarity are beginning to be unraveled, its roles in oth...

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Bibliographic Details
Main Authors: Amalia Riga, Janine Cravo, Ruben Schmidt, Helena R Pires, Victoria G Castiglioni, Sander van den Heuvel, Mike Boxem
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-10-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1009856