Plumbagin induces G2/M arrest and apoptosis and ferroptosis via ROS/p38 MAPK pathway in human osteosarcoma cells

Plumbagin induces G2/M arrest and apoptosis and ferroptosis via ROS/p38 MAPK pathway in human osteosarcoma cells

Plumbagin (PLB), a naphthoquinone compound, has been proven to have anti-cancer properties in different types of cancers. However, the anti-tumor actions as well as molecular processes in osteosarcoma (OS) remain unclear. This study investigates the underlying mechanisms of PLB in human OS cells in...

Full description

Bibliographic Details
Main Authors: Jintang Li, Hang Gao, Ping Wang, Chao Sun, Zhilin Wei, Xingcheng Yi, Shuyuan Yu, Yanan Zhang, Shuqiang Li
Format: Article
Language:English
Published: Elsevier 2024-09-01
Series:Alexandria Engineering Journal
Subjects:
Plumbagin
Osteosarcoma
Apoptosis
Ferroptosis
p38 MAPK
ROS
Online Access:http://www.sciencedirect.com/science/article/pii/S1110016824006021

Internet

http://www.sciencedirect.com/science/article/pii/S1110016824006021

Similar Items