Ribosomal DNA as DAMPs Signal for MCF7 Cancer Cells

Ribosomal DNA as DAMPs Signal for MCF7 Cancer Cells

Introduction: The cell free ribosomal DNA (cf-rDNA) is accrued in the total pool of cell free DNA (cfDNA) in some non-cancer diseases and demonstrates DAMPs characteristics. The major research questions: (1) How does cell free rDNA content change in breast cancer; (2) What type of response in the MC...

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Bibliographic Details
Main Authors: Elena M. Malinovskaya, Elizaveta S. Ershova, Natalya A. Okorokova, Vladimir P. Veiko, Marina S. Konkova, Ekaterina A. Kozhina, Ekaterina A. Savinova, Lev N. Porokhovnik, Serguey I. Kutsev, Nataly N. Veiko, Svetlana V. Kostyuk
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Oncology
Subjects:
DAMPs
human ribosomal gene
rDNA
TLR9
AIM2
cfDNA
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00445/full

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https://www.frontiersin.org/article/10.3389/fonc.2019.00445/full

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