Using a Dual CRISPR/Cas9 Approach to Gain Insight into the Role of LRP1B in Glioblastoma

Using a Dual CRISPR/Cas9 Approach to Gain Insight into the Role of LRP1B in Glioblastoma

<i>LRP1B</i> remains one of the most altered genes in cancer, although its relevance in cancer biology is still unclear. Recent advances in gene editing techniques, particularly CRISPR/Cas9 systems, offer new opportunities to evaluate the function of large genes, such as <i>LRP1B&l...

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Bibliographic Details
Main Authors: Joana Peixoto, Catarina Príncipe, Ana Pestana, Hugo Osório, Marta Teixeira Pinto, Hugo Prazeres, Paula Soares, Raquel T. Lima
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:International Journal of Molecular Sciences
Subjects:
LRP1B
CRISPR/Cas9
glioblastoma
ploidy
secretome
Online Access:https://www.mdpi.com/1422-0067/24/14/11285

Internet

https://www.mdpi.com/1422-0067/24/14/11285

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