Radiation-induced changes in energy metabolism result in mitochondrial dysfunction in salivary glands

Abstract Salivary glands are indirectly damaged during radiotherapy for head and neck cancer, resulting in acute and chronic hyposalivation. Current treatments for radiation-induced hyposalivation do not permanently restore function to the gland; therefore, more mechanistic understanding of the dama...

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Bibliographic Details
Main Authors: Lauren G. Buss, Brenna A. Rheinheimer, Kirsten H. Limesand
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-50877-9