Computational, crystallographic studies, cytotoxicity and anti-tubercular activity of substituted 7-methoxy-indolizine analogues.

Computational, crystallographic studies, cytotoxicity and anti-tubercular activity of substituted 7-methoxy-indolizine analogues.

Indolizines are heteroaromatic compounds, and their synthetic analogues have reportedly showed promising pharmacological properties. In this study, a series of synthetic 7-methoxy-indolizine derivatives were synthesised, characterised and evaluated for in vitro whole-cell anti-tuberculosis (TB) scre...

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Main Authors: Katharigatta Narayanaswamy Venugopala, Sandeep Chandrashekharappa, Melendhran Pillay, Hassan H Abdallah, Fawzi M Mahomoodally, Subhrajyoti Bhandary, Deepak Chopra, Mahesh Attimarad, Bandar E Aldhubiab, Anroop B Nair, Nagaraja Sreeharsha, Mohamed A Morsy, Shinu Pottathil, Rashmi Venugopala, Bharti Odhav, Koleka Mlisana
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0217270

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https://doi.org/10.1371/journal.pone.0217270

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