Interferon-Gamma and Interleukin-1Beta Enhance the Secretion of Brain-Derived Neurotrophic Factor and Promotes the Survival of Cortical Neurons in Brain Injury

Neuro-inflammation is associated with the production of cytokines, which influence neuronal and glial functions. Although the proinflammatory cytokines interferon-γ (IFN-γ) and interleukin-1Beta (IL-1β) are thought to be the major mediators of neuro-inflammation, their role in brain injury remains i...

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Bibliographic Details
Main Authors: Ebtesam M Abd-El-Basset, Muddanna Sakkattu Rao, Ameerah Alsaqobi
Format: Article
Language:English
Published: SAGE Publishing 2020-07-01
Series:Neuroscience Insights
Online Access:https://doi.org/10.1177/2633105520947081