Radiation-Induced Chromosomal Aberrations and Immunotherapy: Micronuclei, Cytosolic DNA, and Interferon-Production Pathway

Radiation-Induced Chromosomal Aberrations and Immunotherapy: Micronuclei, Cytosolic DNA, and Interferon-Production Pathway

Radiation-induced chromosomal aberrations represent an early marker of late effects, including cell killing and transformation. The measurement of cytogenetic damage in tissues, generally in blood lymphocytes, from patients treated with radiotherapy has been studied for many years to predict individ...

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Bibliographic Details
Main Authors: Marco Durante, Silvia C. Formenti
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Oncology
Subjects:
radioimmunotherapy
chromosome aberrations
micronuclei
cyclic GMP–AMP synthase
stimulator of interferon genes
particle therapy
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00192/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2018.00192/full

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