Transcriptional signature of early cisplatin drug-tolerant persister cells in lung adenocarcinoma

Transcriptional signature of early cisplatin drug-tolerant persister cells in lung adenocarcinoma

Resistance to cisplatin is the main cause of treatment failure in lung adenocarcinoma. Drug-tolerant-persister (DTP) cells are responsible for intrinsic resistance, since they survive the initial cycles of treatment, representing a reservoir for the emergence of clones that display acquired resistan...

Full description

Bibliographic Details
Main Authors:	Rodolfo Chavez-Dominguez, Dolores Aguilar-Cazares, Mario Perez-Medina, Santiago Avila-Rios, Maribel Soto-Nava, Alfonso Mendez-Tenorio, Lorenzo Islas-Vazquez, Jesus J. Benito-Lopez, Miriam Galicia-Velasco, Jose S. Lopez-Gonzalez
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-10-01
Series:	Frontiers in Oncology
Subjects:	lung cancer non-small cell lung carcinoma lung adenocarcinoma cisplatin chemotherapy resistance intrinsic resistance
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2023.1208403/full

Similar Items

Role of HMGB1 in Cisplatin-Persistent Lung Adenocarcinoma Cell Lines
by: Rodolfo L. Chavez-Dominguez, et al.
Published: (2021-12-01)

Identification of Mutations Related to Cisplatin-Resistance and Prognosis of Patients With Lung Adenocarcinoma
by: Rui Li, et al.
Published: (2020-10-01)

Transcriptome analysis reveals PRKCA as a potential therapeutic target for overcoming cisplatin resistance in lung cancer through ferroptosis
by: Ting Sun, et al.
Published: (2024-05-01)

The Role of GRP78 on the Resistance to Cisplatin in SPCA-1 Cell Line
by: Long ZHAO, et al.
Published: (2010-01-01)

PD‐0332991 combined with cisplatin inhibits nonsmall cell lung cancer and reversal of cisplatin resistance
by: Minghui Liu, et al.
Published: (2021-03-01)

Research Progress of DNA Methylation in Cisplatin Resistance in Lung Cancer
by: Jinzhe SUN, et al.
Published: (2023-01-01)

Identification of solamargine as a cisplatin sensitizer through phenotypical screening in cisplatin-resistant NSCLC organoids
by: Yi Han, et al.
Published: (2022-08-01)

Advances of DNA Damage Repair and Cisplatin Resistance Mechanisms in Lung Cancer
by: Chunlan TANG, et al.
Published: (2011-12-01)

Screening and Identifying Cisplatin-Related Gene Mutations in Lung Squamous Cell Carcinoma
by: Li X, et al.
Published: (2020-12-01)

Screening of Molecular Markers of Cisplatin Resistance in Lung Adenocarcinoma and Functional Verification Based on TCGA Database
by: WANG Lin, et al.
Published: (2022-06-01)

An epigenomic approach to identifying differential overlapping and cis-acting lncRNAs in cisplatin-resistant cancer cells
by: Olga Vera, et al.
Published: (2018-03-01)

Cisplatin-induced hydroxyl radicals mediate pro-survival autophagy in human lung cancer H460 cells
by: Somruethai Sumkhemthong, et al.
Published: (2021-07-01)

Integrative analysis illustrates the role of PCDH7 in lung cancer development, cisplatin resistance, and immunotherapy resistance: an underlying target
by: Huakang Li, et al.
Published: (2023-07-01)

IL‐25 promotes cisplatin resistance of lung cancer cells by activating NF‐κB signaling pathway to increase of major vault protein
by: Weiming Shen, et al.
Published: (2019-07-01)

MMP9 Expression Correlates With Cisplatin Resistance in Small Cell Lung Cancer Patients
by: Longqiu Wu, et al.
Published: (2022-04-01)

Histone ubiquitination-related gene CUL4B promotes lung adenocarcinoma progression and cisplatin resistance
by: Yanjun Yin, et al.
Published: (2023-11-01)

Autophagy facilitates lung adenocarcinoma resistance to cisplatin treatment by activation of AMPK/mTOR signaling pathway
by: Wu T, et al.
Published: (2015-12-01)

Inhibition of SMYD2 Sensitized Cisplatin to Resistant Cells in NSCLC Through Activating p53 Pathway
by: Lei Shang, et al.
Published: (2019-04-01)

Effect of Dexamethasone on Cisplatin Induced Apoptosis in Primary Cells from Resected Specimens with Chinese Human Lung Adenocarcinoma ex vivo
by: Xueping LIN, et al.
Published: (2010-01-01)

Nanoparticle-Mediated Gene Silencing for Sensitization of Lung Cancer to Cisplatin Therapy
by: Daniel P. Feldmann, et al.
Published: (2020-04-01)

Generation of Stable cisPt Resistant Lung Adenocarcinoma Cells
by: Nico Ruprecht, et al.
Published: (2020-05-01)

Aspirin overcomes cisplatin resistance in lung cancer by inhibiting cancer cell stemness
by: Maoyuan Zhao, et al.
Published: (2020-11-01)

RNA Interference Targeting GRP75 Decreases Cisplatin Resistance in Human Lung Adenocarcinoma Cell
by: Sien SHI, et al.
Published: (2011-04-01)

Mechanistic study of lncRNA UCA1 promoting growth and cisplatin resistance in lung adenocarcinoma
by: Jiali Fu, et al.
Published: (2021-09-01)

Weekly Paclitaxel and Cisplatin in the Treatment of Elderly Advanced Non-small Cell Lung Cancer
by: Ying LIANG, et al.
Published: (2009-10-01)

Characterization of a novel HDAC/RXR/HtrA1 signaling axis as a novel target to overcome cisplatin resistance in human non-small cell lung cancer
by: Wenjing Wang, et al.
Published: (2020-09-01)

Autophagy Inhibition Enhances the Anti-Tumor Activity of Methylseleninic Acid in Cisplatin-Resistance Human Lung Adenocarcinoma Cells
by: Ming Xin, et al.
Published: (2022-05-01)

SOX2 mediates cisplatin resistance in small‐cell lung cancer with downregulated expression of hsa‐miR‐340‐5p
by: Fei Cui, et al.
Published: (2020-05-01)

Successful rechallenge with cisplatin following cisplatin induced ischemic cerebrovascular accident in a patient with small cell lung cancer
by: Farah Rashid, et al.
Published: (2022-10-01)

Effect of PI3K/AKT Pathway on Cisplatin Resistance in Non-small Cell Lung Cancer
by: Yu ZHANG, et al.
Published: (2014-08-01)

Irinotecan/cisplatin versus Etoposide/cisplatin for Patients with Extensive Stage Small Cell Lung Cancer: A Systematic Review
by: Nan YAO, et al.
Published: (2009-08-01)

Melatonin inhibits apoptosis and oxidative tissue damage in cisplatin-induced pulmonary toxicity in rats
by: Lidija Ristić, et al.
Published: (2020-06-01)

Prominin 2 decreases cisplatin sensitivity in non-small cell lung cancer and is modulated by CTCC binding factor
by: Tang Jiyang, et al.
Published: (2023-09-01)

Expression and Significance of Nrf2 and Its Target Genes in Pulmonary Adenocarcinoma A549 Cells Resistant to Cisplatin
by: Kairu ZHANG, et al.
Published: (2009-11-01)

Partners in crime: The feedback loop between metabolic reprogramming and immune checkpoints in the tumor microenvironment
by: Jesus J. Benito-Lopez, et al.
Published: (2023-01-01)

EFFECT OF CHEMOTHERAPY WITH DOCETAXEL / CISPLATIN ON GRANULOCYTIC HEMOPOIESIS IN PATIENTS WITH NON-SMALL CELL LUNG CARCINOMA
by: V. E. Goldberg, et al.
Published: (2016-11-01)

TENS Improves Cisplatin-Induced Neuropathy in Lung Cancer Patients
by: Sanja Tomanovic Vujadinovic, et al.
Published: (2022-10-01)

ARHGAP6 Promotes Apoptosis and Inhibits Glycolysis in Lung Adenocarcinoma Through STAT3 Signaling Pathway
by: Li P, et al.
Published: (2020-10-01)

Integrated analysis reveals critical cisplatin-resistance regulators E2F7 contributed to tumor progression and metastasis in lung adenocarcinoma
by: Xiaomin Mao, et al.
Published: (2024-05-01)

LncRNA-ATB Promotes Cisplatin Resistance in Lung Adenocarcinoma Cells by Targeting the miR-200a/β-Catenin Pathway
by: Tang W, et al.
Published: (2020-03-01)