Allele-specific aberration of imprinted domain chromosome architecture associates with large offspring syndrome

Allele-specific aberration of imprinted domain chromosome architecture associates with large offspring syndrome

Summary: Large offspring syndrome (LOS) and Beckwith-Wiedemann syndrome are similar epigenetic congenital overgrowth conditions in ruminants and humans, respectively. We have reported global loss-of-imprinting, methylome epimutations, and gene misregulation in LOS. However, less than 4% of gene misr...

Full description

Bibliographic Details
Main Authors: Yahan Li, Frimpong Boadu, Max R. Highsmith, Darren E. Hagen, Jianlin Cheng, Rocío Melissa Rivera
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:iScience
Subjects:
Biological sciences
Genetics
molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222005399

Internet

http://www.sciencedirect.com/science/article/pii/S2589004222005399

Similar Items