Nucleotide, Phospholipid, and Kynurenine Metabolites Are Robustly Associated with COVID-19 Severity and Time of Plasma Sample Collection in a Prospective Cohort Study

Nucleotide, Phospholipid, and Kynurenine Metabolites Are Robustly Associated with COVID-19 Severity and Time of Plasma Sample Collection in a Prospective Cohort Study

Understanding the molecular underpinnings of disease severity and progression in human studies is necessary to develop metabolism-related preventative strategies for severe COVID-19. Metabolites and metabolic pathways that predispose individuals to severe disease are not well understood. In this stu...

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Bibliographic Details
Main Authors: Haley A. S. Chatelaine, Yulu Chen, John Braisted, Su H. Chu, Qingwen Chen, Meryl Stav, Sofina Begum, Joann Diray-Arce, Jaleal Sanjak, Mengna Huang, Jessica Lasky-Su, Ewy A. Mathé
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:International Journal of Molecular Sciences
Subjects:
longitudinal cohort
regression analysis
COVID-19 severity
untargeted metabolomics
tryptophan metabolism
phospholipid metabolism
Online Access:https://www.mdpi.com/1422-0067/25/1/346

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https://www.mdpi.com/1422-0067/25/1/346

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