NOX family NADPH oxidases in mammals: Evolutionary conservation and isoform-defining sequences
NADPH oxidases are superoxide-producing enzymes that play a role in host defense, biosynthetic pathways, as well as cellular signaling. Humans have 7 NOX isoforms (NOX1-5, DUOX1,2), while mice and rats lack NOX5 and therefore have only 6 NOX isoforms. Whether all human NOX isoforms or their subunits...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-10-01
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Series: | Redox Biology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231723002525 |