NOX family NADPH oxidases in mammals: Evolutionary conservation and isoform-defining sequences

NADPH oxidases are superoxide-producing enzymes that play a role in host defense, biosynthetic pathways, as well as cellular signaling. Humans have 7 NOX isoforms (NOX1-5, DUOX1,2), while mice and rats lack NOX5 and therefore have only 6 NOX isoforms. Whether all human NOX isoforms or their subunits...

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Bibliographic Details
Main Authors: Bahareh Nazari, Vincent Jaquet, Karl-Heinz Krause
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231723002525