Gene regulation contributes to explain the impact of early life socioeconomic disadvantage on adult inflammatory levels in two cohort studies

Abstract Individuals experiencing socioeconomic disadvantage in childhood have a higher rate of inflammation-related diseases decades later. Little is known about the mechanisms linking early life experiences to the functioning of the immune system in adulthood. To address this, we explore the relat...

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Bibliographic Details
Main Authors: Cristian Carmeli, Zoltán Kutalik, Pashupati P. Mishra, Eleonora Porcu, Cyrille Delpierre, Olivier Delaneau, Michelle Kelly-Irving, Murielle Bochud, Nasser A. Dhayat, Belen Ponte, Menno Pruijm, Georg Ehret, Mika Kähönen, Terho Lehtimäki, Olli T. Raitakari, Paolo Vineis, Mika Kivimäki, Marc Chadeau-Hyam, Emmanouil Dermitzakis, Nicolas Vuilleumier, Silvia Stringhini
Format: Article
Language:English
Published: Nature Portfolio 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-82714-2