Ruthenium–Thymine Acetate Binding Modes: Experimental and Theoretical Studies

Ruthenium complexes have proved to exhibit antineoplastic activity, related to the interaction of the metal ion with DNA. In this context, synthetic and theoretical studies on ruthenium binding modes of thymine acetate (THAc) have been focused to shed light on the structure-activity relationship. Th...

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Bibliographic Details
Main Authors: Silvia Bordoni, Stefano Cerini, Riccardo Tarroni, Magda Monari, Gabriele Micheletti, Carla Boga
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Applied Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3417/11/7/3113