Synthesis, Molecular Docking and Antiplasmodial Activities of New Tetrahydro-β-Carbolines

Malaria is still one of the most dangerous infectious diseases and the emergence of drug resistant parasites only worsens the situation. A series of new tetrahydro-β-carbolines were designed, synthesized by the Pictet–Spengler reaction, and characterized. Further, the compounds were screened for the...

Full description

Bibliographic Details
Main Authors: Anna Jaromin, Beata Gryzło, Marek Jamrozik, Silvia Parapini, Nicoletta Basilico, Marek Cegła, Donatella Taramelli, Agnieszka Zagórska
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/22/24/13569