Antigen Recognition by MR1-Reactive T Cells; MAIT Cells, Metabolites, and Remaining Mysteries
Mucosal-associated Invariant T (MAIT) cells recognize vitamin B-based antigens presented by the non-polymorphic MHC class I related-1 molecule (MR1). Both MAIT T cell receptors (TCR) and MR1 are highly conserved among mammals, suggesting an important, and conserved, immune function. For many years,...
| Hauptverfasser: | , , , |
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| Format: | Artikel |
| Sprache: | English |
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Frontiers Media S.A.
2020-08-01
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| Schriftenreihe: | Frontiers in Immunology |
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| Online Zugang: | https://www.frontiersin.org/article/10.3389/fimmu.2020.01961/full |