Osteogenic induction of asiatic acid derivatives in human periodontal ligament stem cells

Abstract Asiatic acid (AA) and asiaticoside, pentacyclic triterpenoid compounds derived from Centella asiatica, are known for their biological effects in promoting type I collagen synthesis and inducing osteogenesis of stem cells. However, their applications in regenerative medicine are limited due...

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Bibliographic Details
Main Authors: Sirikool Thamnium, Chavee Laomeephol, Prasit Pavasant, Thanaphum Osathanon, Yasuhiko Tabata, Chao Wang, Jittima A. Luckanagul
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-41388-8