Overexpression of FGF2 delays the progression of osteonecrosis of the femoral head activating the PI3K/Akt signaling pathway

Abstract Background The purpose of the current study was to explore the role and underlying mechanism of FGF-2 in dexamethasone (DEX)-induced apoptosis in MC3T3-E1 cells. Methods GSE21727 was downloaded from the Gene Expression Omnibus (GEO) database to identify the differentially expressed genes (D...

Full description

Bibliographic Details
Main Authors: Pei Lu, Yi-min Shen, Ting Hua, Ting Pan, Gang Chen, Teng Dai, Ke-qin Shi
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:https://doi.org/10.1186/s13018-021-02715-9