SCRIB Promotes Proliferation and Metastasis by Targeting Hippo/YAP Signalling in Colorectal Cancer

SCRIB Promotes Proliferation and Metastasis by Targeting Hippo/YAP Signalling in Colorectal Cancer

The complex in which scribble planar cell polarity protein (SCRIB) is located is one of the three main polar protein complexes that play an important role in maintaining epithelial polarity and affecting tumour growth. However, the role of SCRIB in colorectal cancer (CRC) remains largely unknown. Th...

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Bibliographic Details
Main Authors: Hengyang Shen, Changzhi Huang, Jingyu Wu, Jie Li, Tao Hu, Zhenling Wang, Hongqiang Zhang, Yu Shao, Zan Fu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
colorectal cancer
SCRIB
Hippo signaling pathway
tumour invasion and poor prognosis
cell cycle
cell polarity
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.656359/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.656359/full

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