The novel ciliogenesis regulator DYRK2 governs Hedgehog signaling during mouse embryogenesis

The novel ciliogenesis regulator DYRK2 governs Hedgehog signaling during mouse embryogenesis

Mammalian Hedgehog (Hh) signaling plays key roles in embryogenesis and uniquely requires primary cilia. Functional analyses of several ciliogenesis-related genes led to the discovery of the developmental diseases known as ciliopathies. Hence, identification of mammalian factors that regulate cilioge...

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Bibliographic Details
Main Authors: Saishu Yoshida, Katsuhiko Aoki, Ken Fujiwara, Takashi Nakakura, Akira Kawamura, Kohji Yamada, Masaya Ono, Satomi Yogosawa, Kiyotsugu Yoshida
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-08-01
Series:eLife
Subjects:
DYRK2
ciliogenesis
hedgehog signal
development
Online Access:https://elifesciences.org/articles/57381

Internet

https://elifesciences.org/articles/57381

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