Glypican Is a Modulator of Netrin-Mediated Axon Guidance.
Netrin is a key axon guidance cue that orients axon growth during neural circuit formation. However, the mechanisms regulating netrin and its receptors in the extracellular milieu are largely unknown. Here we demonstrate that in Caenorhabditis elegans, LON-2/glypican, a heparan sulfate proteoglycan,...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2015-07-01
|
| Series: | PLoS Biology |
| Online Access: | http://europepmc.org/articles/PMC4493048?pdf=render |