Genetic Deletion of Thorase Causes Purkinje Cell Loss and Impaired Motor Coordination Behavior

Genetic Deletion of Thorase Causes Purkinje Cell Loss and Impaired Motor Coordination Behavior

Thorase belongs to the AAA+ ATPase family, which plays a critical role in maintaining cellular homeostasis. Our previous work reported that Thorase was highly expressed in brain tissue, especially in the cerebellum. However, the roles of Thorase in the cerebellum have still not been characterized. I...

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Bibliographic Details
Main Authors: Chao Li, Han Zhang, Kexin Tong, Menghua Cai, Fei Gao, Jia Yang, Yi Xu, Huaishan Wang, Hui Chen, Yu Hu, Wei He, Jianmin Zhang
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Cells
Subjects:
Thorase
cerebellum
Purkinje cells
neuroinflammation
neurodegenerative disease
Online Access:https://www.mdpi.com/2073-4409/12/16/2032

Internet

https://www.mdpi.com/2073-4409/12/16/2032

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