Serotonin signaling modulates aging-associated metabolic network integrity in response to nutrient choice in Drosophila melanogaster

Lyu et al analysed metabolic network integrity in Drosophila melanogaster to assess the systemic effects of nutrient choice. By knocking out the serotonin receptor, 5-HT2A, they demonstrated that the effects of different macronutrients on the stability of metabolic networks is mediated through serot...

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Dades bibliogràfiques
Autors principals: Yang Lyu, Daniel E. L. Promislow, Scott D. Pletcher
Format: Article
Idioma:English
Publicat: Nature Portfolio 2021-06-01
Col·lecció:Communications Biology
Accés en línia:https://doi.org/10.1038/s42003-021-02260-5
Descripció
Sumari:Lyu et al analysed metabolic network integrity in Drosophila melanogaster to assess the systemic effects of nutrient choice. By knocking out the serotonin receptor, 5-HT2A, they demonstrated that the effects of different macronutrients on the stability of metabolic networks is mediated through serotonin signalling.
ISSN:2399-3642