Comparison of sGC activator and sGC stimulator in 5/6 nephrectomized rats on high-salt-diet

Comparison of sGC activator and sGC stimulator in 5/6 nephrectomized rats on high-salt-diet

IntroductionSoluble guanylate cyclase (sGC) stimulators and activators are known to enhance kidney function in various models of chronic kidney disease (CKD) by increasing cyclic guanosine monophosphate (cGMP). Their differential effects on CKD progression, particularly under conditions of oxidative...

Full description

Bibliographic Details
Main Authors: Xin Chen, Yingquan Xiong, Shufei Zeng, Denis Delić, Mohamed Gaballa, Philipp Kalk, Thomas Klein, Bernhard K. Krämer, Berthold Hocher
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Pharmacology
Subjects:
soluble guanylate cyclase activator
soluble guanylate cyclase stimulator
chronic kidney disease
renal fibrosis
apoptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1480186/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2024.1480186/full

Similar Items