Computational micromodel for epigenetic mechanisms.

Characterization of the epigenetic profile of humans since the initial breakthrough on the human genome project has strongly established the key role of histone modifications and DNA methylation. These dynamic elements interact to determine the normal level of expression or methylation status of the...

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Bibliographic Details
Main Authors: Karthika Raghavan, Heather J Ruskin, Dimitri Perrin, Francois Goasmat, John Burns
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2994705?pdf=render