Computational micromodel for epigenetic mechanisms.
Characterization of the epigenetic profile of humans since the initial breakthrough on the human genome project has strongly established the key role of histone modifications and DNA methylation. These dynamic elements interact to determine the normal level of expression or methylation status of the...
Main Authors: | Karthika Raghavan, Heather J Ruskin, Dimitri Perrin, Francois Goasmat, John Burns |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2994705?pdf=render |
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