D-galacto-D-mannan-mediated Dectin-2 activation orchestrates potent cellular and humoral immunity as a viral vaccine adjuvant

D-galacto-D-mannan-mediated Dectin-2 activation orchestrates potent cellular and humoral immunity as a viral vaccine adjuvant

IntroductionConventional foot-and-mouth disease (FMD) vaccines have been developed to enhance their effectiveness; however, several drawbacks remain, such as slow induction of antibody titers, short-lived immune response, and local side effects at the vaccination site. Therefore, we created a novel...

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Bibliographic Details
Main Authors: Hyeong Won Kim, Mi-Kyeong Ko, So Hui Park, Seokwon Shin, Gang Sik Kim, Dong Yun Kwak, Jong-Hyeon Park, Su-Mi Kim, Jong-Soo Lee, Min Ja Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Immunology
Subjects:
foot-and-mouth disease
D-galacto-D-mannan
Dectin-2 agonist
vaccine adjuvant
cellular and humoral
immune response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1330677/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1330677/full

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