Inhibition of Retrograde Transport Limits Polyomavirus Infection <italic toggle="yes">In Vivo</italic>

Inhibition of Retrograde Transport Limits Polyomavirus Infection <italic toggle="yes">In Vivo</italic>

ABSTRACT Polyomaviruses (PyVs) silently infect most humans, but they can cause life-threatening diseases in immunocompromised individuals. The JC polyomavirus (JCPyV) induces progressive multifocal leukoencephalopathy, a severe demyelinating disease in multiple sclerosis patients receiving immunomod...

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Bibliographic Details
Main Authors: Saumya Maru, Ge Jin, Dhimant Desai, Shantu Amin, Shwetank, Matthew D. Lauver, Aron E. Lukacher
Format: Article
Language:English
Published: American Society for Microbiology 2017-12-01
Series:mSphere
Subjects:
T cells
kidney
mouse
mouse polyomavirus
polyomavirus
retrograde transport
Online Access:https://journals.asm.org/doi/10.1128/mSphereDirect.00494-17

Internet

https://journals.asm.org/doi/10.1128/mSphereDirect.00494-17

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