Role of Per1 and the Mineralocorticoid Receptor in the Coordinate Regulation of αENaC in Renal Cortical Collecting Duct Cells

Renal function and blood pressure exhibit a circadian pattern of variation, but the molecular mechanism underlying this circadian regulation is not fully understood. We have previously shown that the circadian clock protein Per1 positively regulates the basal and aldosterone-mediated expression of t...

Full description

Bibliographic Details
Main Authors: Jacob eRichards, Lauren Ann Jeffers, Sean C All, Kit-Yan eCheng, Michelle L Gumz
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-09-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00253/full