Feasibility of whole genome and transcriptome profiling in pediatric and young adult cancers

Feasibility of whole genome and transcriptome profiling in pediatric and young adult cancers

Cancer whole-genome and transcriptome sequencing (cWGTS) has been challenging to implement in clinical settings. Here, the authors develop a workflow to deliver robust cWGTS analyses and reports within clinically-relevant timeframes for paediatric, adolescent and young adult solid tumour patients.

Bibliographic Details
Main Authors: N. Shukla, M. F. Levine, G. Gundem, D. Domenico, B. Spitzer, N. Bouvier, J. E. Arango-Ossa, D. Glodzik, J. S. Medina-Martínez, U. Bhanot, J. Gutiérrez-Abril, Y. Zhou, E. Fiala, E. Stockfisch, S. Li, M. I. Rodriguez-Sanchez, T. O’Donohue, C. Cobbs, M. H. A. Roehrl, J. Benhamida, F. Iglesias Cardenas, M. Ortiz, M. Kinnaman, S. Roberts, M. Ladanyi, S. Modak, S. Farouk-Sait, E. Slotkin, M. A. Karajannis, F. Dela Cruz, J. Glade Bender, A. Zehir, A. Viale, M. F. Walsh, A. L. Kung, E. Papaemmanuil
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-30233-7

Internet

https://doi.org/10.1038/s41467-022-30233-7

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